Publications

2019

Maria Spano G, Weyn Banningh S, Marshall W, de Vivo L, Bellesi M, Loschky SS, Tononi G, Cirelli C (in press) Sleep deprivation by exposure to novel objects increases synapse density and axon-spine interface in the hippocampal CA1 region of adolescent mice. J Neurosci. doi: 10.1523/JNEUROSCI.0380-19.2019

Albantakis L, Marshall W, Hoel E, Tononi G (2019) What Cause What? A Quantitative Account of Actual Causation Using Dynamical Causal Networks. Entropy, 21(5), 459. doi: 10.3390/e21050459

Rubboli G, Huber R, Tononi G, Tassinari CA (2019) Encephalopathy related to Status Epilepticus during slow Sleep: a link with sleep homeostasis? Epileptic Disord., 21, Supplement 1: 62-70. doi: 10.1684/epd.2019.1059

Baird B, Riedner B, Boly M, Davidson R, Tononi G (2019) Increased lucid dream frequency in long-term meditators but not following MBSR training. Psychology of Consciousness: Theory, Research and Practice, 6(1): 40-54. doi: 10.1037/cns0000176

Bernardi B, Betta M, Cataldi J, Leo A, Haba-Rubio J, Heinzer RC, Cirelli C, Tononi G, Petrini P, Ricciardi, Siclari F (2019) Visual imagery and visual perception induce similar changes in occipital slow waves of sleep. Journal of Neurophysiology, 121: 2140-2152. doi: 10.1152/jn.00085.2019

Cook JD, Eftekari SC, Leavitt LA, Prairie ML, Plante DT (2019) Optimizing Actigraphic Estimation of Sleep Duration in Suspected Idiopathic Hypersomnia. Journal of Clinical Sleep Medicine.,15(04): 597-602.

Plante DT, Cook JD, Barbosa LS, Goldstein MR, Prairie ML, Smith RF, Riedner BA (2019) Establishing the Objective Sleep Phenotype in Hypersomnolence Disorder with and without Comorbid Major Depression. Sleep, Mar 7. doi: 10.1093/sleep/zsz060 [Epub ahead of print]

Lee M, Baird B, Gosseries O, Mieminen JO, Boly M, Postle BR, Tononi G, Lee SW (2019) Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS-EEG study. Sci Rep., 9(1): 5175. doi: 10.1038/s41598-019-41274-2

Bernardi G, Betta M, Ricciardi E, Pietrini P, Tononi G and Siclari F (2019) Regional delta waves in human rapid-eye movement sleep. Journal of Neuroscience, 39(14):2686-2697. doi: 10.1523/JNEUROSCI.2298-18.2019

Tononi G, Cirelli C (2019) Sleep and synaptic down-selection. European Journal of Neuroscience, 0(0): 1-9. doi: 10.1111/ejn.14335

Chang J, Fecchio M, Pigorini A, Massimini M, Tononi G, Van Veen BD (2019) Assessing Recurrent Interactions in Cortical Networks: Modeling EEG Response to Transcranial Magnetic Stimulation. Journal of Neuroscience Methods, 312: 93-104. doi: 10.1016/j.jneumeth.2018.11.006

2018

Cook JD, Eftekari SC, Dallmann E, Sippy M, Plante DT. Ability of the Fitbit Alta HR to quantify and classify sleep in patients with suspected central disorders of hypersomnolence: A comparison against polysomnography (2018) Journal of sleep research. Nov 1:e12789. doi: 10.1111/jsr.12789

Baird B, Castelnovo A, Gosseries O, Tononi G (2018) Frequent lucid dreaming associated with increased functional connectivity between frontopolar cortex and temporoparietal association areas. Scientific Reports, 8(1): 17798. doi: 10.1038/s41598-018-36190-w

Darracq M, Funk CM, Polyakov D, Riedner B, Gosseries O, Nieminen JO, Bonhomme V, Brichant JF, Boly M, Laureys S, Tononi G, Sanders RD. (2018) Evoked Alpha Power is Reduced in Disconnected Consciousness During Sleep and Anesthesia. Scientific reports, 8(1): 16664. doi: 10.1038/s41598-01834957-9

Baird B, Riedner B, Boly M, Davidson R, Tononi G (2018) Increased lucid dream frequency in long-term meditators but not following MBSR training. Psychology of Consciousness: Theory, Research and Practice, November. doi: 10.1037/cns0000176

Garcia Molina G, Tsoneva T, Jasko J, Steele B, Aquino A, Baehr K, Pastoor S, Pfundtner S, Ostrowski L, Miller B, Papas N, Riedner B, Tononi G, White D (2018) Closed-loop system to enhance slow-wave activity. Journal of Neural Engineering, 15(6): 066018.

Siclari F, Bernardi G, Cataldi J, Tononi G (2018) Dreaming in NREM sleep: a high-density EEG study of slow waves and spindles. Journal of Neuroscience, 38(43): 9175-9185. doi: 10.1523/JNEUROSC.0855-18.2018

Dentico D, Bachhuber D, Riedner BA, Ferrarelli F, Tononi G, Davidson RJ, Lutz A (2018) Acute Effects of Meditation Training on the Waking and Sleeping Brain: is it all about homeostasis? European Journal of Neuroscience, 48: 2310-2321. doi: 10.1111/ejn.14131

Sanders R, Banks MI, Darracq M, Moran R, Sleigh J, Gosseries O, Bonhomme V, Brichant JF, Rosanova M, Raz A, Tononi G, Massimini M, Laureys S, Boly M (2018) Propofol-induced unresponsiveness is associated with impaired feedforward connectivity in cortical hierarchy. British Journal of Anaesthesia, 121(5): 1084-1096. doi: 10.1016/j.bja.2018.07.006

Baird B, Castelnovo A, Riedner B, Lutz A, Ferrarelli F, Boly M, Davidson R, Tononi G (2018) Human Rapid Eye Movement Sleep Shows Local Increases in Low-Frequency Oscillations and Global Decreases in High-Frequency Oscillations Compared to Resting Wakefulness. eNeuro, 5(4). doi: 10.1523/ENEURO.0293-18.2018

Bellesi M, de Vivo L, Koebe S, Tononi G, Cirelli C (2018) Sleep and Wake Affect Glycogen Content and Turnover at Perisynaptic Astrocytic Processes. Frontiers in Cellular Neuroscience, 12(308). doi: 10.3389/fncel.2018.00308

Mayner WGP, Marshall W, Albantakis L, Findlay G, Marchman R, Tononi G (2018) PyPhi: A toolbox for integrated information theory. PLoS computational biology, 14(7). doi: 10.1371/journal.pcbi. 1006343

Bourdon AK, Spano GM, Marshall W, Bellesi M, Tononi G, Serra PA, Baghdoyan HA, Lydic R, Campagna SR, Cirelli C (2018) Sleep/wake changes in the metabolome of mouse cortex as revealed by ultra-performance liquid chromatography coupled with high-resolution mass spectrometry. Sci Reports, 8(1): 11225. doi: 1038/s41598-018-29511-6

Bernardi G, Siclari F, Handjaras G, Riedner B, Tononi G (2018) Local and widespread slow waves in stable NREM sleep: Evidence for distinct regulation mechanisms. Frontiers in Human Neuroscience, 12(48): 1-13. doi: 10.3389/fnhum.2018.00248

Honjoh S, Sasai S, Schiereck S, Nagai H, Tononi G & Cirelli C (2018) Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus. Nature Communications, 9(1), 2100. doi: 10.1038/s41467-018-04497-x

Mensen A, Marshall W, Sasai S, Tononi G (2018) Differentiation Analysis of Continuous Electroencephalographic Activity Triggered by Video Clip Contents. Journal of Cognitive Neuroscience, 30(8): 1108-1118. doi: 10.1162/jocn_a_01278

Marshall W, Albantakis L, Tononi G (2018) Black-boxing and cause-effect power. PLOS Computational Biology, 14(4). doi: 10.1371/journal.pcbi.1006114

Sanders RD, Mostert N, Lindroth H, Tononi G, Sleigh J (2018) Is consciousness frontal? Two perioperative case reports that challenge that concept. British Journal of Anaesthesia, 121(1): 330-332. doi: 10.1016/j.bja.2018.01.010

Massimini M, Tononi G (2018) Sizing Up Consciousness: Towards an Objective Measure of the Capacity for Experience. Oxford University Press.

Bellesi M, Haswell JD, de Vivo L, Marshall W, Roseboom PH, Tononi G, Cirelli C (2018) Myelin modifications after chronic sleep loss in adolescent mice. Sleep, 41(5). doi: 10.1093/sleep/zsy034

D’Agostino A, Castelnovo A, Cavallotti S, Casetta C, Marcatili M, Gambini O, Canevini M, Tononi G, Riedner B, Ferrarelli F, Sarasso S (2018) Sleep endophenotypes of schizophrenia: slow waves and sleep spindles in unaffected first-degree relatives. NPJ schizophrenia, 4(1):2. doi: 10.1038/s41537-018-0045-9

Cook JD, Prairie ML, Plante DT (2018)  Ability of the Multisensory Jawbone UP3 to Quantify and Classify Sleep in Patients with Suspected Central Disorders of Hypersomnolence: A comparison against polysomnography and actigraphy.  J Clin Sleep Med, 14(5):841-8. doi: 10.5664/jcsm.7120

Plante DT, Birn RM, Walsh EC, Hoks RM, Cornejo MD, Abercrombie HC (2018) Reduced resting-state thalamostriatal functional connectivity is associated with excessive daytime sleepiness in persons with and without depressive disorders. J Affect Disord, 227:517-20.

Abercrombie HC, Frost CP, Walsh EC, Hoks RM, Cornejo MD, Sampe MC, Geffey AE, Plante DT, Ladd CO, Birn RM (2018) Neural signaling of cortisol, childhood emotional abuse, and depression-related memory bias.  Biol Psychiatry Cogn Neurosci Neuroimaging, 3(3):274-84.

Plante DT (2018) Nocturnal sleep architecture in idiopathic hypersomnia: a systematic review and meta-analysis. Sleep Med, 45:17-24.

2017

Cook JD, Prairie ML, Plante DT (2017) Utility of the Fitbit Flex to evaluate sleep in major depressive disorder: a comparison against polysomnography and wrist-worn actigraphy. Journal of affective disorders, 217:299-305.

Marshall W, Kim H, Walker SI, Tononi G, Albantakis L (2017) How causal analysis can reveal autonomy in models of biological systems. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 375(2109). doi: 10.1098/rsta.2016.0358

Lee M, Sanders RD, Yeom SK, Won DO, Seo KS, Kim HJ, Tononi G & Lee S-W (2017) Network Properties in Transitions of Consciousness during Propofol-induced Sedation. Scientific Reports, 7(1):16791. doi: 10.1038/s41598-017-15082-5

Boly M, Massimini M, Tsuchiya N, Postle BR, Koch C, Tononi G (2017) Are the Neural Correlates of Consciousness in the Front or in the Back of the Cerebral Cortex? Clinical and Neuroimaging Evidence. The Journal of Neuroscience, 37(40): 9603-13. doi: 10.1523/jneurosci.3218-16.2017

Nir Y, Andrillon T, Marmelshtein A, Suthana N, Cirelli C, Tononi G, Fried I (2017) Selective neuronal lapses precede human cognitive lapses following sleep deprivation. Nature Medicine, 23: 1474-1480. doi: 10.1038/nm.4433

Funk CM, Peelman K, Bellesi M, Marshall W, Cirelli C, Tononi G (2017) Role of somatostatin-positive cortical interneurons in the generation of sleep slow waves. J Neurosci, 37 (38): 9132-48. doi: 10.1523/JNEUROSCI.1303-17.2017

Cirelli C, Tononi G (2017) The Sleeping Brain. Cerebrum, June issue. PMID: 28698776.

Bellesi M, de Vivo L, Chini M, Gilli F, Tononi G, Cirelli C (2017) Sleep loss promotes astrocytic phagocytosis and microglial activation in mouse cerebral cortex. J Neurosci, 37(21): 5263-5273. doi: 10.1523/JNEUROSCI.3981-16.2017.

Siclari F, Baird B, Perogamvros L, Bernardi G, LaRoque J, Riedner B, Boly M, Postle BR, Tononi G. (2017) The neural correlates of dreaming. Nature Neuroscience, 20:872-878. doi: 10.1038/nn.4545

Siclari F, Tononi G (2017) Local aspects of sleep and wakefulness. Current Opinion in Neurobiol., 44: 222-227. doi: https://doi.org/10.1016/j.conb.2017.05.008

Boly M, Jones B, Findlay G, Plumley E, Mensen A, Hermann B, Tononi G, Maganti R. (2017) Altered sleep homeostasis correlates with cognitive impairment in patients with focal epilepsy. Brain: a journal of neurology, 140(4): 1026-40. doi: 10.1093/brain/awx017

Bodart O, Gosseries O, Wannez S, Thibaut A, Annen J, Boly M, Rosanova M, Casali A, Casarotto S, Tononi G, Massimini M, Laureys S. (2017) Measures of metabolism and complexity in the brain of patients with disorders of consciousness. NeuroImage: Clinical, 14: 354-62. doi: 10.1016/j.ncil.2017.02.002

de Vivo L, Bellesi M, Marshall W, Bushong EA, Ellisman MH, Tononi G, Cirelli C (2017) Ultrastructural evidence for synaptic scaling across the wake/sleep cycle. Science, 355(6324): 507-10. doi: 10.1126/science.aah5982

Nagai H, de Vivo L, Chilardi MF, Tononi G, Cirelli C (2017) Sleep Consolidates Motor Learning of Complex Motor Sequences in Mice. Sleep, 40 (2). doi: 10.1093/sleep/zsw059.

Cirelli C (2017) Sleep, synaptic homeostasis, and neuronal firing rates. Curr Opin Neurobiol., 44: 72-79.

Allada R, Cirelli C, Sehgal A (2017) Molecular mechanisms of sleep homeostasis in flies and mammals. CSH Perspectives, Apr 21. pii: a027730. doi: 10.1101/cshperspect.a027730.

Kurth S, Riedner BA, Dean DC, O’Muircheartaigh J, Huber R, Jenni OG, Deoni SCL, LeBourgeois MK (2017) Traveling slow oscillations during sleep: A marker of brain connectivity in childhood. Sleep, Sep 1;40(9).

Plante DT, Cook JD, Goldstein MR (2017) Objective measures of sleep duration and continuity in major depressive disorder with comorbid hypersomnolence: a primary investigation with contiguous systematic review and meta‐analysis. Journal of sleep research, 26(3):255-65.

Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE (2017) Longitudinal associations of hypersomnolence and depression in the Wisconsin Sleep Cohort Study. Journal of affective disorders, 207:197-202.